Around 170 phytoconstituents isolated from 110 plants belonging to 55 families have been reported to possess hepatoprotective activity. The hepatoprotective activity of these plants is based on lowering liver biomarkers as well as suppressing of degenerative changes in hepatocytes produced by. According to the literature 10 anethum graveolens 9 l. Pdf liver, being an important body organ, plays a vital role in metabolism. Hepatoprotective activity, mechanism of action, medicinal plants, herbal, and treatment. Hepatoprotective activity of some medicinal plants in sudan hindawi. Around 160 active constituents from 101 plants are claimed to have post liver protecting activity. Investigation of medicinal plants for hepatoprotective activity thesis submitted to partial fulfillment for the award of degree of doctor of philosophy in p harmacy submitted by p.
In india, more than 93 medicinal plants are used in different combinations in the preparations of 40 patented herbal formulations 7. Hepatoprotective activity of some medicinal plants in sudan. Plants contain active constituents known as phytochemicals, which have been tested for their hepatoprotective potential in many parts of the world. View antioxidant and hepatoprotective activity of medicinal plants research papers on academia. Standardization of some hepatoprotective medicinal plants. Hence, herbal drugs have become increasingly popular and their use is widespread.
The hepatoprotective effect of the methanol extract of maytenus royleanus leaves mem. Medicinal plants with hepatoprotective activity in iranian folk medicine majid asadisamani1, najme kafashfarkhad2, nafiseh azimi3, ali fasihi4, ebrahim aliniaahandani2, mahmoud rafieiankopaei1 1medical plants research center, shahrekord university of medical sciences, shahrekord, iran. Pdf advances in hepatoprotective medicinal plants research. Generally, it was of particular importance to notice that antioxidant, antitumor, cytotoxicity, antibacterial, and antiviral activities. Maytenus royleanus celastraceae is a medicinal plant, possesses antioxidant and anticancer activities. There are a number of medicinal combinations in the iranian traditional medicine which are commonly used as tonic for liver. Hepatoprotective activities of two ethiopian medicinal plants. Hepatoprotective activity of the medicinal plants name of plant source or family plant parts used hepatotoxic inducing agents extracts studied biochemical and histopathological parameters studied boerhaavia diffusa. Scrophulariaceae used in ethiopian traditional medical practices for the treatment of liver diseases. Active extracts, fractions or mixture of fractionsextracts may prove very effective drugs.
Hepatoprotective activity of some indigenous plants. Different medicinal herbs and plants extracts have potent hepatoprotective activity in various animal models. Hepatoprotective activity of medicinal plants thesis proposal. The present study evaluated the in vivo hepatoprotective activity of two medicinal plants, namely, justicia schimperiana hochst. Pdf hepatoprotective activity of some plants extract. Many medicinal plants used for a range of ailments and disorders contain vts as their active principles.
Evaluation of the cytotoxic activity of extracts from medicinal plants used for the treatment of malaria in kagera and lindi regions, tanzania. Developing countries are reliant on medicinal plants as their main source of treatment for diseases. Parmar and others published hepatoprotective activity of some plants extract against paracetamol induced hepatotoxicity in wistar rats find, read and cite all the. Comparative hepatoprotective activities of selected indian. In india, quite eighty seven plants square measure used in 33 patented propitiatory multiingredient plant formulations.
R siddhartha college of pharmaceutical sciences, vijayawada, andhra pradesh, india. Look at some indian medicinal plants for hepatoprotective activity g. The action of these plants is largely attributed to their phytoconstituents such as flavonoids, antioxidant, and antiinflammatory effects. In ayurveda, an ancient system of indian medicine, numerous plant formulations and combined extracts of plants are used as drug of. Employed by an writing company phd thesis on hepatoprotective activity find bargain crafting a resume. Treatment, causes and applications of medicinal plants as therapeutic agents meagan thompson, yogini jaiswal, ilya wang, leonard williams abstract hepatotoxicity, or liver damage, is caused by hepatotoxins, which may source from chemicals, dietary supplements, pharmaceutical drugs, and medicinal plants. Therefore a large number of plants and formulations have been claimed to have hepatoprotective activity so the development of.
We have evaluated the hepatoprotective effect of an ethanoli. Jul 07, 2004 moringa oleifera lam moringaceae, commonly known as drumstick, is used in indian folk medicine for the treatment of various illness. The plant kingdom is a valuable source of new herbal medicinal agents. Antioxidant and hepatoprotective activities of some saudi medicinal plants essam abdelsattar1, naglaa shehab1, fathalla harraz2, salah ghareib3 1department of pharmacognosy, faculty of pharmacy, cairo university, 11562 cairo, egypt 2department of pharmacognosy, faculty of pharmacy, alexandria university, alexandria, egypt. Hepatotoxicity and the role of some herbal hepatoprotective plants. Carbon tetrachloride, hepatoprotection, paracetamol, psidium guajava, thioacetamide liver diseases, such as jaundice, cirrhosis and fatty liver are very common worldwide. Pdf medicinal plants with hepatoprotective activity in. The present study reports the investigation done on the hepatoprotective activity of ethanolic extract of mikania scandens l. Pdf medicinal plants possessed hepatoprotective activity. Hepatoprotective and antioxidant activity of ipomoea staphylina linn ramachandran jeyadevi1, devanesan arul ananth2 and thilagar sivasudha1 abstract background. But till date there is no evidence regarding the evaluation of hepatoprotective activity of the methanolic extract of terminalia arjuna stem bark and its constituent flavonoids against ccl 4. Allium sativum the antihepatic toxicity of garlic was investigated experimentally in rats, crcl3 alone increased serum levels of ast and alt.
There were two sets of criteria applied to articles for inclusion in this. Traditional medicines and prescriptions with beneficial effects. A recent update on hepatoprotective potential of herbal plant. D763600004 vinayaka missions university salem tamilnadu, india,he. It plays an important role to maintaining various physiological processes in the body. Antioxidant and hepatoprotective activity of medicinal.
The studies on medicinal plants should not be manufacture of plant products should be governed restricted to find new prototype pure compounds by standards of safety and efficacy. Search terms consisted of medicinal plants, traditional medicine, folk medicine, hepatoprotective, iran, liver, therapeutic uses, compounds. B 250 mgkg and 500 mgkg produced p dec 06, 2012 hepatoprotective activity, types of liver disease, signs and symptoms of the liver disease, liver diseases and medicinal plants, hepatoprotective allopathic treatment, ursodeoxycholic acid ursodiol, penicillamine, plants used in the treatmentt of liver disease hepatoprotective natural plants, some of herbal formulations used in liver disorder, evaluation of hepatoprotective activity. Hence, herbal drugs have become increasingly popular and their use is wide spread. However, only a small proportion of hepatoprotective plants as well as. The aim of present study was to assess the hepatoprotective activities of total phenylethanoid glycosides from a.
In india, numerous medicinal plants are used for the treatment of liver disorders. A large number of plants and formulations have been claimed to show hepatoprotective activities. In vitro hepatoprotective activity of terminalia arjuna stem. Medicinal plants as hepatoprotective agents in indian systems.
In modern day therapeutics, hepatoprotective activity of various medicinal plants and their formulations are gaining renewed interest. A great challenge to health care professionals and pharmaceutical. Pdf evaluation of the cytotoxic activity of extracts. Phenylethanoid glycosides are one of main components in a. In vitro assays revealed a variety of significant biological activities of polyphenolic plant extracts. About 100 relevant articles were extracted after a narrow search for a combination of the keywords and subsequent analysisper the inclusion criteria. Abstract the present study deals with comparative evaluation of hepatoprotective activities of melia azedarach. Pdf hepatoprotective activity of some plants extract against. In early study we have shown that peptides obtained from 7 plantain plantago major l. Medicinal plants possessed hepatoprotective activity 27 body weight in rats protect liver enzymes, oxidation status mda and gsh, fucosidase tumor marker and risk lipid ratio1112. Willd ms and its ethyl acetate and nhexane fractions in isoniazid. Medicinal plants as hepatoprotective agents in indian systems of medicine.
Advances in hepatoprotective medicinal plants research article pdf available in bangladesh journal of pharmacology 123. The hepatoprotective activity is probably due to the presence of flavonoids, phenolic compounds, polyphenols etc in all few herbal plants. Hepatic useful new compounds for the development of effe. In recent years numerous traditional medicinal plants were tested for their hepatoprotective potential in the experimental animals. Hepatotoxicity was induced in male wistar rats by intraperitoneal injection of carbon tetrachloride 0. These plants are widely used in traditional medicine especially in rural areas for their effectiveness, availability, and cheap prices. Medicinal plants possessed hepatoprotective activity. Many in vitro and in vivo studies have been reported regarding the assessment of hepatoprotective activity of terminalia arjuna 1224. Choudhary 2 institute of pharmacy 1, niet, greater noida 206, uttar pradesh, india. Introduction liver is the largest gland and one of the vital organs of the body. Considerable studies have been carried out on ethno medicinal plants. Medicinal plants with hepatoprotective activity in iranian. Ptrospermum acerifolium kanak champa the hepatoprotective activity of the ethanol extract of the leaf of ptrospermum acerifolium sterculiaceae was investigated in rats. Hepatoprotective activity of ethanol extract of conyza b.
969 1478 1321 824 1284 466 602 284 721 393 1462 197 318 209 894 439 903 753 586 1219 30 605 652 959 533 1233 250 1327 1197 1148 356 567 558 1028 593